In 2004 Ford introduced the new F-150 and set the mark for front suspensions in the light duty pick up segment by converting to a front strut design with the suspension action being supported by a coil mounted on a strut. Eventually Dodge and GM would follow suit. You can lower the front of this truck using either coil, a strut or, if it's a 2WD model, a spindle. The 4WD versions use "basically" the same strut other than they limit the down travel so that it can't contact the drive axle. DJM also released a lower control arm that allows you to low the front by relocating the lower strut mount. They are available in 2 or 3 inch drop but only list the 2 inch for the 4WD trucks although I know several people running the 3 inch ones on their 4WD trucks with no issues.
The rear suspension uses leaf springs and can be lowered 2 inches with shackles (or 3 inches if it's a 4WD, then you can pull the block for an extra inch) but if you want to go down farther than that then you need to do a flip kit due to the hanger being integrated into the frame. Rear drops are available in 4 to 7 inches.